"What replication in the laboratory are you referring to? There is no such work. It is all smoke and mirrors, with lots of bombast. Macroevolution is mere speculation, based on zero hard evidence. No living person was alive during ages past, and all we have to go on are fossil remains."
Any evolutionary change from speciation or above is macroevolution. Take some time to read about observed instances of speciation before saying macroevolution is mere speculation.
Another good resource on macroevolution is here. Clearly there is more than simply fossil evidence for macroevolution.